<p class="jove_content">Gallium(III) 5,10,15-(tris)pentafluorophenylcorrole and its freebase analogue exhibit low micromolar cell cytotoxicity. This manuscript describes an RNA transcription reaction, imaging RNA with an ethidium bromide-stained gel, and quantifying RNA with UV-Vis spectroscopy, in order to assess transcription inhibition by corroles and demonstrates a straightforward method of evaluating anticancer candidate properties.</p>

an-vitro-enzymatic-assay-to-measure-transcription-inhibition-gallium

Institution - Beckman Research Institute of the City of Hope

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