This study identified the core targets and pathways of shikonin against RCC via multimethod analysis and in vitro validation, providing a framework for further mechanistic studies.

screening-mechanism-shikonin-against-renal-cell-carcinoma-via-network

Screening the Mechanism of Shikonin Against Renal Cell Carcinoma via Network Pharmacology, Molecular Docking, and Cellular Experimental Verification

Renal cell carcinoma (RCC) is one of the most common tumors in the urinary system and has the highest mortality rate. Previous investigations have ...

Multi-omics profiling of Buti Huatan Tang (BTHTT) in chronic obstructive pulmonary disease reveals its potential to modulate the IL-1R2/IL-1&#946;-thyroid hormone metabolic axis. This work provides a framework for further mechanistic validation of the bioactive components of BTHTT, establishing a foundation for future causal intervention studies required to confirm this axis.

integrative-multi-omics-analysis-buti-huatan-tang-chronic-obstructive

Integrative Multi-omics Analysis of Buti Huatan Tang in Chronic Obstructive Pulmonary Disease

This study utilized a multi-omics and computational biology framework to investigate the therapeutic potential of the Traditional Chinese Medicine (TCM) ...

Institution - Mudanjiang Normal University

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