<p class="jove_content">Here we present a protocol to develop a dominant-negative inducible system, in which any protein can be conditionally inactivated by reversibly overexpressing a dominant-negative mutant version of it.</p>

inducible-and-reversible-dominant-negative-dn-protein-inhibition

Inducible and Reversible Dominant-negative (DN) Protein Inhibition

Dominant-negative (DN) protein inhibition is a powerful method to manipulate protein function and offers several advantages over other genome-based ...

Institution - Creighton University School of Dentistry

Articles Published in JoVE