<p class="jove_content">This article describes the generation of an orthotopic mouse model of human pleural mesothelioma by implantation of H2052/484 mesothelioma cells into the pleural cavity of immunocompromised athymic mice. The longitudinal monitoring of the development of intrapleural tumors was assessed by non-invasive multimodal [<sup>18</sup>F]-2-fluoro-2-deoxy-D-glucose positron emission tomography and computed tomography imaging.</p>

implantation-monitoring-petct-an-orthotopic-model-human-pleural

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice

Malignant pleural mesothelioma (MPM) is a rare and aggressive tumor arising in the mesothelium that covers the lungs, the heart, and the thoracic cavity. ...

MicroPET/SPECT/CT Imaging Laboratory

Institution - University Hospitals and University of Geneva

Articles Published in JoVE