<p class="jove_content">In this protocol, we described a new method to study the influence of glial cell heterogeneity on axon growth with an <em>in vitro</em> co-culture system. Rat cortical glial cells were cultured to confluence and cocultured with highly purified rat dorsal root ganglia neurons. Different glial cell influence on neurons adhesion and axon growth was compared directly in the same culture. This method provides a new way to directly study the glial cell heterogeneity influence on neuron adhesion and axon growth.
</p>

study-glial-cell-heterogeneity-influence-on-axon-growth-using-new

Study Glial Cell Heterogeneity Influence on Axon Growth Using a New Coculture Method

In the central nervous system of all mammals, severed axons after injury are unable to regenerate to their original targets and functional recovery is ...

Institution - Fourth Military Medical Univeristy

Articles Published in JoVE