<p class="jove_content">We provide an improved protocol for extracting high molecular weight DNA from hypersaline microbial mats. Microbial cells are separated from the mat matrix prior to DNA extraction and purification.  This enhances the concentrations, quality, and size of the DNA. The protocol may be used for other refractory samples.</p>

extraction-of-high-molecular-weight-dna-from-microbial-mats

Extraction of High Molecular Weight DNA from Microbial Mats

Successful and accurate analysis and interpretation of metagenomic data is dependent upon the efficient extraction  of high-quality, high molecular weight ...

Institution - Arnold School of Public Health, University of South Carolina

Articles Published in JoVE