<p class="jove_content">The hyperinsulinemic-euglycemic clamp, or insulin clamp, is the gold standard for assessing insulin action <em>in vivo</em>.  A method for performing insulin clamps in mice is described.  This includes a method for arterial catheterization that permits experiments to be performed in conscious, unrestrained mice with minimal stress.</p>

hyperinsulinemic-euglycemic-clamps-in-conscious-unrestrained-mice

Hyperinsulinemic-euglycemic Clamps in Conscious, Unrestrained Mice

Type 2 diabetes is characterized by a defect in insulin action. The hyperinsulinemic-euglycemic clamp, or insulin clamp, is widely considered the "gold ...

Institution - Sanford-Burnham Medical Research Institute at Lake Nona

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