<p class="jove_content">Early detection of apoptosis may identify at-risk cell populations in a variety of diseases.  Here we demonstrate a method to link an early apoptosis-detection protein (Annexin V) to a MRI-detectable iron oxide nanoparticle (SPIO).  This method may be extended to other proteins of interest to generate MRI-detectable molecular imaging probes.</p>

synthesis-of-an-in-vivo-mri-detectable-apoptosis-probe

Synthesis of an <em>In vivo</em> MRI-detectable Apoptosis Probe

Cellular apoptosis is a prominent feature of many diseases, and this programmed cell death typically occurs before clinical manifestations of disease are ...

Institution - Stanford University Medical Center

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