<p class='jove_content'>Here, we present a simple method for performing fluorescence DNA <em>in situ</em> hybridization (DNA ISH) to visualize repetitive heterochromatic sequences on slide-mounted chromosomes. The method requires minimal reagents and it is versatile for use with short or long probes, different tissues, and detection with fluorescence or non-fluorescence-based signals.</p>

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Institution - Claremont McKenna, Pitzer, and Scripps Colleges

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