<p class='jove_content'>The transfer of bm12 lymphocytes into a C57BL/6 recipient is an established model of systemic lupus erythematosus. Here we describe how to initiate disease using this model and how to characterize T follicular helper cells, germinal center B cells and plasma cells by flow cytometry.</p>

the-bm12-inducible-model-systemic-lupus-erythematosus-sle-c57bl6

The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice

Systemic lupus erythematosus (SLE) is an autoimmune disease with diverse clinical and immunological manifestations. Several spontaneous and inducible ...

Institution - Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine

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