<p class='jove_content'>We propose a simple self-assembly technique of silica colloidal nanoparticles to create a nanofluidic junction between two microchannels in polydimethylsiloxane (PDMS). Using this technique, a nanoporous bead membrane with a pore size down to ~45 nm was built inside a microchannel and applied to electrokinetic preconcentration of DNA samples.</p>

creating-sub-50-nm-nanofluidic-junctions-pdms-microfluidic-chip-via

Institution - New York University Tandon School of Engineering

Articles Published in JoVE