<p class="jove_content">Restenosis following cardiovascular procedures (bypass surgery, angioplasty, or stenting) is a significant problem reducing the durability of these procedures. An ideal therapy would inhibit smooth muscle cell (VSMC) proliferation while promoting regeneration of the endothelium. We describe a model for simultaneous assessment of VSMC proliferation and endothelial function in vivo.</p>

murine-aortic-crush-injury-an-efficient-vivo-model-smooth-muscle-cell

Murine Aortic Crush Injury: An Efficient <em>In Vivo</em> Model of Smooth Muscle Cell Proliferation and Endothelial Function

Arterial reconstruction, whether angioplasty or bypass surgery, involves iatrogenic trauma causing endothelial disruption and vascular smooth muscle cell ...

Institution - Baltimore Veterans Affairs Medical Center

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