<p class='jove_content'>Modeling human brain development has been hindered due to the unprecedented complexity of neural epithelial tissue. Here, a method for the robust generation of brain organoids to delineate early events of human brain development and to model microcephaly <em>in vitro</em> is described. </p>

generation-ipsc-derived-human-brain-organoids-to-model-early

Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders

The restricted availability of suitable in vitro models that can reliably represent complex human brain development is a significant bottleneck that ...

Institution - Medical School of University of Cologne

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