<p class="jove_content">Here we describe a protocol for employing high-throughput RNAi screening to uncover host targets that can be manipulated to enhance oncolytic virus therapy, specifically rhabodvirus and vaccinia virus therapy, but it can be readily adapted to other oncolytic virus platforms or for discovering host genes that modulate virus replication generally.</p>

genome-wide-rnai-screening-to-identify-host-factors-that-modulate

Institution - Children's Hospital of Eastern Ontario (CHEO) Research Institute

Articles Published in JoVE