<p class="jove_content">Here, we present a reliable and straightforward two-dimensional (2D) coculture system for studying the interaction between tumor cells and bone marrow adipocytes, which reveals a dual effect of melanoma cell-derived factors on the bone marrow adipocytes differentiation and also poses a classic method for the mechanistic study of bone metastasis.</p>

dual-effects-melanoma-cell-derived-factors-on-bone-marrow-adipocytes

Institution - Yongchuan Hospital of Chongqing Medical University

Articles Published in JoVE