<p class="jove_content">We describe the use of optogenetics and electrophysiological recordings for selective manipulations of hippocampal theta oscillations (5-10 Hz) in behaving mice. The efficacy of the rhythm entrainment is monitored using local field potential. A combination of opto- and pharmacogenetic inhibition addresses the efferent readout of hippocampal synchronization.</p>

optogenetic-entrainment-hippocampal-theta-oscillations-behaving

Optogenetic Entrainment of Hippocampal Theta Oscillations in Behaving Mice

Extensive data on relationships of neural network oscillations to behavior and organization of neuronal discharge across brain regions call for new tools ...

Institution - Leibniz Institute for Molecular Pharmacology (FMP)/ NeuroCure Cluster of Excellence

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