<p class="jove_content">Here we present an effective method to investigate the antifibrotic activity of intravenously infused human mesenchymal stromal cells obtained from the whole umbilical cord following the induction of lung injury by an endotracheal injection of bleomycin in C57BL/6 mice. This protocol can be easily extended to the preclinical testing of other therapeutics.</p>

induction-of-mouse-lung-injury-by-endotracheal-injection-of-bleomycin

Induction of Mouse Lung Injury by Endotracheal Injection of Bleomycin

Pulmonary fibrosis is a hallmark of several human lung diseases with a different etiology. Since current therapies are rather limited, mouse models ...

Institution - Azienda Socio Sanitaria Territoriale (ASST) Papa Giovanni XXIII

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