<p class="jove_content">This protocol presents a technique for high-resolution mapping of replication sites in structurally preserved chromatin <em>in situ</em> that employs a combination of pre-embedding EdU-streptavidin-Nanogold labeling and ChromEMT.</p>

imaging-replicative-domains-ultrastructurally-preserved-chromatin

Imaging Replicative Domains in Ultrastructurally Preserved Chromatin by Electron Tomography

Principles of DNA folding in the cell nucleus and its dynamic transformations that occur during the fulfillment of basic genetic functions (transcription, ...

Institution - V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology

Articles Published in JoVE