<p class="jove_content">Here, a simple protocol is presented for producing mRNA nanoparticles based on poly(beta aminoester) polymers, easy to be tailored by changing the encapsulated mRNA. The workflow for synthesizing the polymers, the nanoparticles, and their <em>in vitro</em> essential characterization are also described. A proof-of-concept regarding immunization is also added.</p>

synthesis-characterization-mrna-loaded-poly-beta-aminoesters

Synthesis and Characterization of mRNA-Loaded Poly(Beta Aminoesters) Nanoparticles for Vaccination Purposes

Vaccination has been one of the major successes of modern society and is indispensable in controlling and preventing disease. Traditional vaccines were ...

Institution - Universitat Ramon Llull (URL)

Articles Published in JoVE