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<p class="jove_content">We present a protocol to measure the elastic moduli of collagen-rich areas in normal and diseased liver using atomic force microscopy. The simultaneous use of polarization microscopy provides high spatial precision for localizing collagen-rich areas in the liver sections.</p>

measurement-liver-stiffness-using-atomic-force-microscopy-coupled

Measurement of Liver Stiffness Using Atomic Force Microscopy Coupled with Polarization Microscopy

Matrix stiffening has been recognized as one of the key drivers of the progression of liver fibrosis. It has profound effects on various aspects of cell ...

Institution - Czech-BioImaging IPHYS, Institute of Physiology of the Czech Academy of Sciences

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