<p class="jove_content">Here we describe a detailed protocol to generate highly enriched cultures of astrocytes derived from different regions of the central nervous system of postnatal mice and their direct conversion into functional neurons by the forced expression of transcription factors.</p>

isolation-and-direct-neuronal-reprogramming-of-mouse-astrocytes

Isolation and Direct Neuronal Reprogramming of Mouse Astrocytes

Direct neuronal reprogramming is a powerful approach to generate functional neurons from different starter cell populations without passing through ...

Department of Physiological Genomics

Biomedical Center Munich

Institution - Ludwig-Maximilians University

Articles Published in JoVE