Pulmonary Ejection Time

Pulmonary ejection time is the interval during which the right ventricle ejects blood through the pulmonary valve into the pulmonary artery, making it a useful measure of right-sided cardiac function. In Doppler echocardiography, clinicians measure the time from the onset of forward pulmonary blood flow to its cessation, while ventricular contraction opens the valve and generates flow into the pulmonary circulation. Interpreted with heart rate and other hemodynamic findings, pulmonary ejection time can help assess right ventricular performance and pulmonary vascular conditions, including pulmonary hypertension, and can support cardiovascular research and noninvasive physiological assessment.

Pulmonary Ejection Time - Related Videos

Research

JoVE Journal - Biology

Evaluation of Right Ventricular Function in Experimental Models of Pulmonary Arterial Hypertension

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2025

The presentation of detailed methods for the evaluation of right ventricle function will enhance the quality and reliability of pulmonary hypertension research, offering a robust framework for future studies and enhancing reproducibility across different laboratories.

Establishment and Validation of a Rat Model of Pulmonary Arterial Hypertension Associated with Pulmonary Fibrosis

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2025

Here, the method of inducing pulmonary arterial hypertension associated with pulmonary fibrosis (PF-PH) rat model by injecting bleomycin into the airway is introduced. We also provide a step-by-step approach to validate this animal model.

Pulmonary Structural MRI using Free-Breathing, Self-Gated Ultra-short Echo Time Imaging

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2024

A protocol is described for generating high-resolution structural images of the lungs using ultra-short-echo time (UTE) Magnetic Resonance Imaging (MRI). This protocol allows for images to be acquired using a simple MRI pulse sequence during free-breathing.

Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery

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Cited by 8 •

2017

The following protocol describes the methodology for the acquisition and analysis of echocardiographic images used to obtain the Left Atrial Volume (LAV), Aorta (Ao) diameter, and Pulmonary Artery (PA) diameter in mice. This technique is a non-invasive, non-terminal procedure that allows assessment of the cardiopulmonary function.

Research

JoVE Journal - Medicine
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A Murine Model of Hyperlipidemia-Induced Heart Failure with Preserved Ejection Fraction

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Cited by 2 •

2024

This protocol presents a detailed approach to replicating a murine model of hyperlipidemia-induced heart failure with preserved ejection fraction (HFpEF). The design combines the administration of adeno-associated virus 9-cardiac troponin T-low-density lipoprotein receptor (AAV9-cTnT-LDLR) and poloxamer-407 (P-407).

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