Handedness
Handedness - Related Videos
07:06
Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury
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Cited by 1 •
2025
The block-building task provides a rapid, objective, quantitative measurement of how often individuals choose to use their left versus right hand for reach-to-grasp action. After unilateral peripheral nerve injury, patients often shift to near-total usage of one hand, the direction of which is not predictable from other clinical factors.
05:36
Central and Divided Visual Field Presentation of Emotional Images to Measure Hemispheric Differences in Motivated Attention
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2017
This study compared central versus divided visual field presentations of emotional images to assess differences in motivated attention between the two hemispheres. The late positive potential (LPP) was recorded using electroencephalography (EEG) and event-related potentials (ERPs) methodologies to assess motivated attention.
08:55
Cryo-Electron Tomography Remote Data Collection and Subtomogram Averaging
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Cited by 1 •
2022
The present protocol describes high-resolution cryo-electron tomography remote data acquisition using Tomo5 and subsequent data processing and subtomogram averaging using emClarity. Apoferritin is used as an example to illustrate detailed step-by-step processes to achieve a cryo-ET structure at 2.86 Å resolution.
10:32
Development of a Virtual Reality Assessment of Everyday Living Skills
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Cited by 25 •
2014
A challenge for proving treatment efficacy for cognitive impairments in schizophrenia is finding the optimizing measurement of skills related to everyday functioning. The Virtual Reality Functional Capacity Assessment Tool (VRFCAT) is an interactive gaming based computerized measure aimed at skills associated with everyday functioning, including baseline impairments and treatment related changes.
11:31
Functional Near Infrared Spectroscopy of the Sensory and Motor Brain Regions with Simultaneous Kinematic and EMG Monitoring During Motor Tasks
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Cited by 17 •
2014
Monitoring brain activity during upright motor tasks is of great value when investigating the neural source of movement disorders. Here, we demonstrate a protocol that combines functional near infrared spectroscopy with continuous monitoring of muscle and kinematic activity during 4 types of motor tasks.
FAQs
Enantiomers can share molecular connectivity yet behave differently because their three-dimensional arrangements present different spatial patterns to chiral partners. Those interactions can alter how a molecule is recognized or how it reacts, even though the mirror-image forms contain the same connected groups. This principle helps explain differences in odor, biological effects, and reactivity.
Recognition can depend on the spatial relationship between a molecule and another chiral molecule. Two mirror-image forms may therefore make unequal contacts with the same partner, producing different degrees or types of interaction. In chemistry, this makes handedness relevant when explaining selective behavior in molecular recognition, rather than treating connectivity alone as sufficient.
Analytical behavior can differ between mirror-image forms, so identifying a molecule only by its connectivity may not fully describe how it appears in a measurement. Chemists address this distinction with spectroscopy and chiral separation, approaches that help identify or distinguish handed forms. This is especially important when a sample’s chemical behavior depends on stereochemical identity.
Chemists match the approach to the task: spectroscopy helps identify handedness, chiral separation distinguishes forms, and stereoselective synthesis controls which form is produced. Used together, these methods connect structural identification with practical control. The combination is useful when a research goal requires both recognizing the existing stereochemical form and obtaining a desired one.
Stereoselective synthesis is most relevant when chemists need to control the handed form generated during preparation rather than separate forms after they have been made. That control can matter wherever enantiomers show different reactivities, biological effects, or odors. It therefore provides a route for incorporating stereochemical control into molecular design and chemical production.
In pharmaceutical chemistry, handedness matters because mirror-image forms may produce different biological effects. Chemists can use stereoselective synthesis to control which form is made, chiral separation to distinguish forms, and spectroscopy to identify them. These tools help connect molecular three-dimensional arrangement with the biological behavior considered during pharmaceutical research.
The same stereochemical principles extend beyond pharmaceuticals to catalysis, materials science, and molecular recognition. In each area, researchers may need to identify a handed form, control its formation, or understand how it interacts with another chiral molecule. The relevant emphasis changes by application, but the central concern remains linking three-dimensional arrangement to chemical behavior.