Bluetooth-enabled Stimulator

A Bluetooth-enabled stimulator is a device that delivers controlled electrical stimulation while receiving operating commands wirelessly through Bluetooth communication. In neuroscience, a paired computer or mobile interface can set or adjust stimulation parameters, and the device converts those instructions into timed pulses delivered through electrodes to neural tissue or experimental preparations. These systems support repeatable studies of neural excitability, circuit function, and neuromodulation while reducing tethering during experiments. Wireless control can improve flexibility in behavioral, physiological, and translational neuroscience research by enabling researchers to deliver precisely timed stimulation during freely moving or otherwise remote measurements.

Bluetooth-enabled Stimulator - Related Videos

Research

JoVE Journal - Neuroscience

A Simple Stimulatory Device for Evoking Point-like Tactile Stimuli: A Searchlight for LFP to Spike Transitions

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Cited by 4 •

2014

To elucidate the complex transition from Local Field Potentials (LFPs) to spikes a suitable stimulator for light mechanical peripheral stimuli was built. As an application, the spiking activities recorded from somatosensory cortex were analyzed by a multi-objective optimization strategy. The results demonstrated that the proposed stimulator was able to deliver tactile stimuli with millisecond and millimeter precisions.

Research

JoVE Journal - Immunology and Infection
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Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade

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Cited by 9 •

2011

This paper describes a simple technique to induce alloantigen-specific anergy in human peripheral blood mononuclear cells. The technique can be applied clinically to generate non-alloreactive donor cells. Infusion of these cells could improve immune reconstitution and reduce toxicity after allogeneic hematopoietic stem cell transplantation.

Research

JoVE Journal - Biology
Free Sample

BEST: Barcode Enabled Sequencing of Tetrads

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Cited by 4 •

2014

Barcode Enabled Sequencing of Tetrads (BEST) replaces the manual processes of isolating, disrupting and spacing tetrads. BEST isolates tetrads by fluorescence-activated cell sorting onto agar plates, separates the spores by agitation with glass beads, and determines which randomly arrayed colonies were derived from the same original tetrad using molecular barcodes.

FIBS-enabled Noninvasive Metabolic Profiling

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2014

A description of how to calibrate Förster Resonance Energy Transfer integrated biological sensors (FIBS) for in situ metabolic profiling is presented. The FIBS can be used to measure intracellular levels of metabolites noninvasively aiding in the development of metabolic models and high throughput screening of bioprocess conditions.

Research

JoVE Journal - Behavior

Non-aversive Animal Restraint Enabling Recording of Optomotor Reflex in Ground Squirrels

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Cited by 1 •

2025

The protocol describes how to measure the optomotor response in 13-lined ground squirrels, a cone-dominant species with retinal features resembling the human macula. The platform design enhances handling and reduces anxiety, improving the animal's ability to stay on the raised platform, enabling non-invasive assessment of changes in visual function.

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