Intracortical Electrodes

Intracortical electrodes are small conductive interfaces implanted within the cerebral cortex to record or modulate neural activity, making them important tools in bioengineering and neural prosthetics. Their electrode contacts detect extracellular voltage changes produced by nearby neurons, while controlled electrical currents can stimulate cortical tissue; signal-processing systems then translate recorded activity into digital commands. Microelectrode arrays support studies of cortical function and enable brain-computer interfaces that can control robotic limbs, computer cursors, or other assistive devices. Ongoing research aims to improve signal quality, biocompatibility, long-term stability, and safe integration with neural tissue.

Intracortical Electrodes - Related Videos

Research

JoVE Journal - Bioengineering

Tools for Surface Treatment of Silicon Planar Intracortical Microelectrodes

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Cited by 3 •

2022

The present protocol describes tools for handling silicon planar intracortical microelectrodes during treatments for surface modification via gas deposition and aqueous solution reactions. The assembly of the components used to handle the devices throughout the procedure is explained in detail.

Intracortical Inhibition Within the Primary Motor Cortex Can Be Modulated by Changing the Focus of Attention

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Cited by 21 •

2017

Using two different transcranial magnetic stimulation (TMS) protocols, this manuscript describes how to measure and compare cortical inhibition within the primary motor cortex when adopting different attentional foci.

Implanting an On-Head Electrode System in a Rat Model for Real-Time Seizure Detection

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2025

This video demonstrates the method of implanting an on-head electrode system in an anesthetized rat for real-time seizure detection. The procedure includes placing stimulation and recording electrodes, securing them with dental cement, and connecting them to a head-mounted amplifier.

Brain Mapping Using a Graphene Electrode Array

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2023

We present a graphene array-based brain mapping procedure to reduce the invasiveness and improve spatiotemporal resolution. Graphene array-based surface electrodes exhibit long-term biocompatibility, mechanical flexibility, and suitability for brain mapping in a convoluted brain. This protocol allows for constructing multiple forms of sensory maps simultaneously and sequentially.

Education

JoVE Core - Chemistry

Standard Electrode Potentials

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2020

On comparing the reactivity of silver and lead, it is observed that the two ionic species, Ag+ (aq) and Pb2+ (aq), show a difference in their redox reactivity towards copper: the silver ion undergoes spontaneous reduction, while the lead ion does not. This relative redox activity can be easily quantified in electrochemical cells by a property called cell potential. This property is commonly known as cell voltage in electrochemistry, and it is a measure of the energy which accompanies the charge...

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