Mechanical Failure

Mechanical failure is the loss of a component’s ability to safely support loads or perform its intended function, often resulting from excessive stress, deformation, fracture, wear, or material degradation. It occurs when applied forces exceed a material’s strength or when repeated loading initiates and propagates fatigue cracks; instability such as buckling can also cause sudden failure. In bioengineering, analyzing mechanical failure helps assess implants, prostheses, tissue-engineering scaffolds, and medical devices exposed to physiological forces and environments. Failure analysis guides material selection, structural design, testing, and safety improvements, supporting more durable devices and reducing risks to patients.

Mechanical Failure - Related Videos

Research

JoVE Journal - Engineering

Imaging of the Microstructural Failure Mechanism in the Human Hip

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Cited by 1 •

2023

The protocol enables the measurement of the deformation of the bone microstructure in the entire proximal human femur and its toughness by combining large-volume micro-CT scanning, a custom-made compressive stage, and advanced image processing tools.

A Virtual Simulation Experiment of Mechanics: Material Deformation and Failure Based on Scanning Electron Microscopy

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2023

This work presents a three-dimensional virtual simulation experiment for material deformation and failure that provides visualized experimental processes. Through a set of experiments, users can become familiar with the equipment and learn the operations in an immersive and interactive learning environment.

In Situ Time-dependent Dielectric Breakdown in the Transmission Electron Microscope: A Possibility to Understand the Failure Mechanism in Microelectronic Devices

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Cited by 1 •

2015

The time-dependent dielectric breakdown (TDDB) in on-chip interconnect stacks is one of the most critical failure mechanisms for microelectronic devices. This paper demonstrates the procedure of an in situ TDDB experiment in the transmission electron microscope, which opens a possibility to study the failure mechanism in microelectronic products.

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models

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2023

The present protocol describes obtaining the pressure-volume relationship through transesophageal pacing, which serves as a valuable tool in evaluating diastolic function in mouse models of heart failure.

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation

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Cited by 5 •

2023

Right ventricular failure and functional tricuspid regurgitation are associated with left-sided heart disease and pulmonary hypertension, which contribute significantly to morbidity and mortality in patients. Establishing a chronic ovine model to study right ventricular failure and functional tricuspid regurgitation will help in understanding their mechanisms, progression, and possible treatments.

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