Peg Microgels
Peg Microgels - Related Videos
04:58
Embedded Bioprinting of Tissue-like Structures Using κ-Carrageenan Sub-Microgel Medium
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Cited by 3 •
2024
This study introduces a novel κ-carrageenan sub-microgel suspension bath, displaying remarkable reversible jamming-unjamming transition properties. These attributes contribute to the construction of biomimetic tissues and organs in embedded 3D bioprinting. The successful printing of heart/esophageal-like tissues with high resolution and cell growth demonstrates high-quality bioprinting and tissue engineering applications.
07:50
Electrophysiology of Scorpion Peg Sensilla
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Cited by 3 •
2011
This article describes an electrophysiological method for isolating chemical stimulation to individual sensilla via extracellular, tip-recordings under mineral oil.
11:34
Controlled Synthesis and Fluorescence Tracking of Highly Uniform Poly(N-isopropylacrylamide) Microgels
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Cited by 5 •
2016
Non-stirred precipitation polymerization provides a rapid, reproducible prototyping approach to the synthesis of stimuli-sensitive poly(N-isopropylacrylamide) microgels of narrow size distribution. In this protocol synthesis, light scattering characterization and single particle fluorescence tracking of these microgels in a wide-field microscopy setup are demonstrated.
06:41
A Peg Plate Biofilm Assay for Screening Antibacterial Agents
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2025
This video demonstrates an assay for screening antimicrobial compounds that efficiently eliminate biofilms using a peg-plate. The methodology monitors the biofilm's metabolic state after treatment with antimicrobial compounds, facilitating the determination of the minimum biofilm eradication concentration.
09:11
Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release
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Cited by 10 •
2016
We present a facile method to fabricate a biodegradable gelatin-based drug release platform that is magneto-thermally responsive. This was achieved by incorporating superparamagnetic iron oxide nanoparticles and poly(N-isopropylacrylamide-co-acrylamide) within a spherical gelatin micro-network crosslinked by genipin, in conjunction with an alternating magnetic field application system.
FAQs
Their crosslinked polymer networks provide a design framework in which water uptake and microscale structure can be adjusted alongside stiffness, porosity, and degradation. These variables influence how particles behave as carriers or biomaterial building blocks. In bioengineering, controlling them helps connect material architecture with intended cellular or molecular responses.
Functional groups on PEG microgels provide chemical handles for further modification and cargo loading. They can also support presentation of biochemical cues, allowing the particle interface to be tailored for biological interactions. This is important when the same platform must combine a defined material environment with added molecular signals in cell or tissue engineering studies.
Porosity and degradation are useful design variables because they can be controlled rather than treated as fixed features. Adjusting these characteristics helps researchers tailor the microgels for different roles, including cargo carriers, cell culture scaffolds, or components of larger biomaterials. Their inclusion links material persistence and structure to the intended bioengineering application.
A practical workflow begins by identifying the intended role, such as cargo delivery, cell culture, tissue engineering, or assembly into an injectable material. Researchers can then select and tune particle size, stiffness, porosity, degradation, functional groups, and biochemical cues. This application-driven approach connects measurable material properties with the desired biological or structural outcome.
Water-swollen polymer networks and modifiable functional groups make PEG microgels suitable for loading drugs and proteins. Their particle size, porosity, degradation, and chemical presentation can be engineered to fit different carrier designs. This tunability supports bioengineering strategies that seek more precise control over how therapeutic cargo is incorporated into a material system.
PEG microgels can serve as scaffolds whose stiffness, porosity, degradation, and biochemical cues are adjusted for a biological setting. Their microscale structure helps connect material design with cell and molecular behavior, while functional groups allow additional modification. These features support their use in cell culture, tissue engineering, and regenerative biomaterial development.