Stroke Survivors

Stroke survivors are people recovering from or living with the consequences of a stroke, a disruption of brain blood flow that can impair movement, sensation, speech, cognition, or independence. After injury, surviving neural circuits may reorganize, while weakness, altered muscle control, and reduced feedback can limit purposeful movement and everyday function. Bioengineering applies this understanding to develop rehabilitation robots, wearable sensors, neuroprosthetic devices, and brain-computer interfaces that measure performance, deliver targeted assistance, or translate neural signals into control commands. These technologies support personalized therapy, objective progress tracking, and new strategies for restoring function and participation in daily life.

Stroke Survivors - Related Videos

Research

JoVE Journal - Neuroscience

The Mouse Stroke Unit Protocol with Standardized Neurological Scoring for Translational Mouse Stroke Studies

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2025

This article presents a protocol for executing the highly translational and independently proven mouse Stroke Unit (mSU) concept in large-stroke mice. It also provides a standardized protocol for executing the focal experimental stroke scale in mice, which evaluates stroke focal deficits detected even long-term.

Research

JoVE Journal - Medicine
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Modeling Stroke in Mice: Permanent Coagulation of the Distal Middle Cerebral Artery

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Cited by 103 •

2014

Various murine models of middle cerebral artery occlusion (MCAO) are widely used in experimental brain research. Here, we demonstrate the model of transcranial permanent distal MCAO which produces consistent cortical infarction of a size corresponding to damage imposed by the majority of human ischemic strokes.

Modeling Stroke in Mice: Transient Middle Cerebral Artery Occlusion via the External Carotid Artery

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Cited by 16 •

2021

Different models of middle cerebral artery occlusion (MCAo) are used in experimental stroke research. Here, an experimental stroke model of transient MCAo via the external carotid artery (ECA) is described, which aims to mimic human stroke, in which the cerebrovascular thrombus is removed due to spontaneous clot lysis or therapy.

A Preclinical Model of Exertional Heat Stroke in Mice

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Cited by 21 •

2021

The protocol describes the development of a standardized, repeatable, preclinical model of exertional heat stroke (EHS) in mice free from adverse external stimuli such as electric shock. The model provides a platform for mechanistic, preventative, and therapeutic studies.

Exertional Heat Stroke Mouse Model: A Protocol to Study Mechanisms Underlying Exertional Heat Stroke

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2025

In this video we describe a step-by-step protocol to study exertional heat stroke (EHS) in a mouse model.

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