Density Matrix Reconstruction

Density matrix reconstruction is the process of estimating a quantum system’s density matrix, the mathematical object that describes its state, including statistical mixtures and measurement uncertainty. It works by collecting measurement outcomes across selected bases or observables and using those data to infer matrix elements through linear inversion, optimization, or maximum-likelihood estimation, while enforcing physical constraints such as unit trace and positive semidefiniteness. In engineering, this form of quantum state tomography characterizes qubits, sensors, photonic systems, and other quantum devices. The reconstructed state supports performance validation, noise analysis, calibration, error mitigation, and the development of reliable quantum technologies.

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Research

JoVE Journal - Behavior

Cortical Source Analysis of High-Density EEG Recordings in Children

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Cited by 7 •

2014

In recent years, there has been increasing interest in estimating the cortical sources of scalp measured electrical activity for cognitive neuroscience experiments. This article describes how high density EEG is acquired and how recordings are processed for cortical source estimation in children from the age of 2 years at the London Baby Lab.

Research

JoVE Journal - Cancer Research

Non-Destructive Evaluation of Regional Cell Density Within Tumor Aggregates Following Drug Treatment

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Cited by 8 •

2022

The present protocol develops an image-based technique for rapid, non-destructive, and label-free regional cell density and viability measurement within 3D tumor aggregates. Findings revealed a cell-density gradient, with higher cell densities in core regions than outer layers in developing aggregates and predominantly peripheral cell death in HER2+ aggregates treated with Trastuzumab.

Research

JoVE Journal - Medicine
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Three-Dimensional Reconstruction of Orbital Fractures

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Cited by 2 •

2025

Personalized medicine for orbital reconstruction is developing rapidly. Due to the delicate nature of the orbit, small discrepancies following fracture reconstruction may cause impairment in visual perception. Here, we describe three methods for virtual 3D reconstruction of orbital defects and their indications and potential pitfalls for correct reconstruction.

Education

JoVE Core - Biology

The Extracellular Matrix

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2026

In order to maintain tissue organization, many animal cells are surrounded by structural molecules that make up the extracellular matrix (ECM). Together, the molecules in the ECM maintain the structural integrity of tissue as well as the remarkable specific properties of certain tissues.Composition of the Extracellular MatrixThe extracellular matrix (ECM) is commonly composed of ground substance, a gel-like fluid, fibrous components, and many structurally and functionally diverse molecules.

Density Gradient Ultracentrifugation

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2023

Density gradient ultracentrifugation is a common technique used to isolate and purify biomolecules and cell structures. This technique exploits the fact that, in suspension, particles that are more dense than the solvent will sediment, while those that are less dense will float. A high-speed ultracentrifuge is used to accelerate this process in order to separate biomolecules within a density gradient, which can be established by layering liquids of decreasing density in a centrifuge tube. The...

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