Lossless Line

A lossless line is an ideal transmission line that transfers electromagnetic energy without attenuation, making it a fundamental model in electrical and communications engineering. Its conductors are treated as having zero resistance and its dielectric as having zero conductance, so distributed inductance and capacitance govern wave propagation without dissipating power; voltage and current vary along the line according to its characteristic impedance and phase constant. This model supports analysis of reflection, standing waves, impedance matching, and signal propagation at high frequencies. Although real cables exhibit losses, the lossless approximation helps engineers design and evaluate transmission systems, microwave circuits, antennas, and interconnects.

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Research

JoVE Journal - Bioengineering

Lensless Fluorescent Microscopy on a Chip

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Cited by 8 •

2011

A lensless on-chip fluorescent microscopy platform is demonstrated that can image fluorescent objects over an ultra-wide field-of-view of e.g., >0.6-8 cm2 with <4μm resolution using a compressive sampling based decoding algorithm. Such a compact and wide-field fluorescent on-chip imaging modality could be valuable for high-throughput cytometry, rare-cell research and microarray-analysis.

Lensless On-chip Imaging of Cells Provides a New Tool for High-throughput Cell-Biology and Medical Diagnostics

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Cited by 26 •

2009

Lensfree on-chip imaging and characterization of cells is illustrated. This on-chip cell imaging approach provides a compact and cost-effective tool for medical diagnostics and high-throughput cell biology applications, making it especially suitable for resource poor settings.

Assessing Cell Viability and Death in 3D Spheroid Cultures of Cancer Cells

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Cited by 35 •

2019

Here, we present several simple methods for evaluating viability and death in 3D cancer cell spheroids, which mimic the physico-chemical gradients of in vivo tumors much better than the 2D culture. The spheroid model, therefore, allows evaluation of the cancer drug efficacy with improved translation to in vivo conditions.

Network Analysis of the Default Mode Network Using Functional Connectivity MRI in Temporal Lobe Epilepsy

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Cited by 35 •

2014

The Default Mode Network (DMN) in Temporal Lobe Epilepsy (TLE) is analyzed in the resting state of the brain using seed-based functional connectivity MRI (fcMRI).

Real-time Breath Analysis by Using Secondary Nanoelectrospray Ionization Coupled to High Resolution Mass Spectrometry

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Cited by 8 •

2018

A protocol for characterizing chemical composition of exhaled breath in real time by using secondary nanoelectrospray ionization coupled to high resolution mass spectrometry is demonstrated.

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