Vortex Mixer

A vortex mixer is a laboratory device that rapidly blends liquids or resuspends material in small containers, making it a routine tool for reproducible sample preparation. Its motor drives an eccentric rotating mechanism that transfers circular motion to a cup or platform, generating a vortex in the liquid when a tube contacts the mixer; mixing intensity depends on contact and operating conditions. In bioengineering, vortex mixers combine reagents, dissolve solutes, resuspend cell pellets, and homogenize suspensions before assays or downstream processing. Consistent mixing improves sample uniformity, supports reliable measurements, and helps standardize workflows involving biological and biochemical materials.

Vortex Mixer - Related Videos

Research

JoVE Journal - Bioengineering
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Microfluidic Mixers for Studying Protein Folding

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Cited by 9 •

2012

In this work we explain the fabrication and use of a microfluidic mixer capable of mixing two solutions in ~8 μs. We also demonstrate the use of these mixers with spectroscopic detection using UV fluorescence and fluorescence resonance energy transfer (FRET).

Research

JoVE Journal - Bioengineering
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Synthesizing Lipid Nanoparticles by Turbulent Flow in Confined Impinging Jet Mixers

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Cited by 21 •

2024

A detailed protocol for synthesizing lipid nanoparticles (LNPs) using confined impinging jet (CIJ) mixer technologies, including a two-jet CIJ and a four-jet multi-inlet vortex mixer (µMIVM), is demonstrated. The CIJ mixers generate reproducible, turbulent micro-mixing environments, resulting in the production of monodisperse LNPs.

Research

JoVE Journal - Environment
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Implementation of a Hyperbolic Vortex Plasma Reactor for the Removal of Micropollutants in Water

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2025

This study presents the methodology for the generation of six different types of plasma discharges within a Hyperbolic Vortex Plasma Reactor for the degradation of micropollutants in water, including pharmaceuticals and per- and polyfluoroalkyl substances (PFAS).

Research

JoVE Journal - Bioengineering

Microscale Vortex-assisted Electroporator for Sequential Molecular Delivery

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Cited by 2 •

2014

A microfluidic vortex assisted electroporation platform was developed for sequential delivery of multiple molecules into identical cell populations with precise and independent dosage control. The system’s size based target cell purification step preceding electroporation aided to enhance molecular delivery efficiency and processed cell viability.

Education

JoVE Science Education - Engineering

Flow Visualization in a Water Tunnel: Observing the Leading-edge Vortex Over a Delta Wing

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2023

Source: Jose Roberto Moreto, Gustaaf Jacobs and Xiaofeng Liu, Department of Aerospace Engineering, San Diego State University, San Diego, California The delta wing, shown in Figure 1D, is a popular design in high-speed airplanes due to its superb performance in transonic and supersonic flight regimes. This type of wing has a small aspect ratio and high sweep angle, which reduces drag at high subsonic, transonic and supersonic flight regimes. The aspect ratio is defined as the wing span divided...

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