Embryonic Development

Embryonic development is the biological process through which a fertilized egg becomes a multicellular embryo with organized tissues, organs, and body structures. It begins with rapid cell division and continues through coordinated processes such as cell differentiation, migration, proliferation, and programmed cell death, guided by genetic signals and interactions among neighboring cells. In biology, studying embryonic development reveals how body plans form and how cellular communication shapes tissue organization. Research in this field supports understanding congenital disorders, stem cell behavior, evolution, and regenerative medicine, while experimental models help investigate how environmental factors and genetic changes influence development.

Embryonic Development - Related Videos

Research

JoVE Journal - Biology

A System for ex vivo Culturing of Embryonic Pancreas

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Cited by 24 •

2012

Here, we describe a method for isolation, culture and manipulation of mouse embryonic pancreas. This represents an excellent ex vivo system for studying various aspects of pancreatic development, including morphogenesis, differentiation and growth. Pancreatic bud explants can be cultured for several days and used in a range of different applications, including whole-mount immunofluorescence and live imaging.

Research

JoVE Journal - Developmental Biology
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Analysis of Cardiomyocyte Development using Immunofluorescence in Embryonic Mouse Heart

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Cited by 9 •

2015

Mutations that lead to congenital heart defects benefit from in vivo investigation of cardiac structure during development, but high-resolution structural studies in the mouse embryonic heart are technically challenging. Here we present a robust immunofluorescence and image analysis method to assess cardiomyocyte-specific structures in the developing mouse heart.

Cell Labeling and Injection in Developing Embryonic Mouse Hearts

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Cited by 4 •

2014

We describe a series of methods to inject dyes, DNA vectors, virus, and cells in order to monitor both cell fate and phenotype of endogenous and grafted cells derived from embryonic or pluripotent cells within mouse embryos at embryonic day (E)9.5 and later stages of development.

Blastomere Explants to Test for Cell Fate Commitment During Embryonic Development

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Cited by 15 •

2013

The fate of an individual embryonic cell can be influenced by inherited molecules and/or by signals from neighboring cells. Utilizing fate maps of the cleavage stage Xenopus embryo, single blastomeres can be identified for culture in isolation to assess the contributions of inherited molecules versus cell-cell interactions.

Optical Sectioning and Visualization of the Intervertebral Disc from Embryonic Development to Degeneration

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2021

We present a method to investigate spatial chondrocyte organization in the anulus fibrosus of the intervertebral disc using an optical sectioning method.

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