Extrusion-based Printing

Extrusion-based printing is an additive manufacturing technique that builds three-dimensional structures by depositing material through a nozzle, making it valuable for fabricating customized biological constructs. In bioengineering, pneumatic, piston, or screw-driven systems force bioinks or other printable materials through the nozzle in programmed paths, where successive layers maintain their shape through viscosity, cooling, or crosslinking. The method supports controlled placement of polymers, hydrogels, and living cells to produce tissue-engineering scaffolds, drug-delivery devices, and models of biological structures. By tuning nozzle size, flow rate, and printing conditions, researchers can adjust resolution, mechanical properties, and cell compatibility for regenerative medicine and laboratory research.

Extrusion-based Printing - Related Videos

Research

JoVE Journal - Engineering

Data Communication Based on MQTT in a Polymer Extrusion Process

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Cited by 1 •

2022

This work proposes a flexible method for data communication between a film extrusion system and monitoring devices based on a message protocol called Message Queuing Telemetry Transport (MQTT).

Education

JoVE Science Education - Engineering

Demonstration of the Power Law Model Through Extrusion

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2023

Source: Kerry M. Dooley and Michael G. Benton, Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA Polymer melts are often formed into simple shapes or "extrudates", such as cylindrical pellets, flat sheets, or pipe, using an extruder.1 Polyolefins are among the most common extrudable polymers. Extrusion involves transporting and melting solid feed, which is sometimes mixed with non-polymeric materials, and the pressure build-up and transport of the melt or mixture.

Four-Dimensional Printing of Stimuli-Responsive Hydrogel-Based Soft Robots

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Cited by 4 •

2023

This manuscript describes a 4D printing strategy for fabricating intelligent stimuli-responsive soft robots. This approach can provide the groundwork to facilitate the realization of intelligent shape-transformable soft robotic systems, including smart manipulators, electronics, and healthcare systems.

Live Imaging of Cell Extrusion from the Epidermis of Developing Zebrafish

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Cited by 20 •

2011

Dying cells are extruded from epithelial tissues by concerted contraction of neighboring cells without disrupting barrier function. The optical clarity of developing zebrafish provides an excellent system to visualize extrusion in living epithelia. Here we describe methods to induce and image extrusion in the larval zebrafish epidermis at cellular resolution.

Research

JoVE Journal - Chemistry
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Sediment Core Extrusion Method at Millimeter Resolution Using a Calibrated, Threaded-rod

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Cited by 21 •

2016

An extrusion method using a calibrated threaded-rod is presented, which allows for mm scale subsampling of aquatic sediment cores. Millimeter-scale sampling is necessary to fully characterize recent event stratigraphy in sediment records.

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