Droplet Interaction Force

Droplet interaction force is the mechanical force exchanged when liquid droplets approach, collide, deform, coalesce, or separate, making it important for predicting multiphase flow behavior. During an interaction, inertia and viscous stresses drive droplet motion and deformation, while surface tension resists changes in shape; a thin liquid film between droplets can also generate lubrication forces that delay or prevent coalescence. Engineers study these interactions in sprays, emulsions, microfluidic systems, inkjet printing, and coating processes. Measuring or modeling the forces helps control droplet size, collision outcomes, transport, and product uniformity in industrial and research applications.

Droplet Interaction Force - Related Videos

Research

JoVE Journal - Biochemistry

Real-Time Force Measurement Between Emulsion Droplets During Enzymatic Breakdown

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2025

This protocol employs dual-trap optical tweezers to measure inter-droplet forces in real time during the enzymatic digestion of emulsions. It facilitates the study of emulsion stability and droplet dynamics, with applications in food science and pharmaceuticals.

Measuring the Interaction Force Between a Droplet and a Super-hydrophobic Substrate by the Optical Lever Method

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2019

The protocol aims to investigate the interaction between droplets and super-hydrophobic substrates in the air. This includes calibrating the measurement system and measuring the interaction force at super-hydrophobic substrates with different grid fractions.

Biomembrane Force Probe to Quantitate Receptor-Ligand Interactions

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2025

In this video, biomembrane force probes (BFPs) are used to measure the forces between receptors and ligands. This technique can detect interactions by monitoring the pressure needed to break the bonds between the pMHC conjugated on the probe beads and the TCRs on the target cells.

Education

JoVE Core - Chemistry

Intermolecular Forces

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2020

Atoms and molecules interact through bonds (or forces): intramolecular and intermolecular. The forces are electrostatic as they arise from interactions (attractive or repulsive) between charged species (permanent, partial, or temporary charges) and exist with varying strengths between ions, polar, nonpolar, and neutral molecules. The different types of intermolecular forces are ion–dipole, dipole–dipole, hydrogen bonds, and dispersion; among these, dipole–dipole, hydrogen bonds, and dispersion...

Research

JoVE Journal - Cancer Research

Exploring the Regulation of Lipid Droplet Catabolism through Lipophagy

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2025

Lipophagy is a selective form of autophagy that involves the degradation of lipid droplets. Dysfunctions in this process are associated with cancer development. However, the precise mechanisms are not yet fully understood. This protocol describes quantitative imaging approaches to better understand the interplay between autophagy, lipid metabolism, and cancer progression.

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