Magnetic resonance imaging (MRI) remains one of the most versatile and powerful noninvasive imaging modalities in modern research and clinical practice, enabling detailed structural, functional, and molecular characterization of biological systems without ionizing radiation. Continuous advances in hardware, pulse sequence design, acquisition strategies, and computational analysis have expanded MRI well beyond conventional anatomical imaging, making it indispensable across neuroscience, oncology, cardiology, musculoskeletal research, and preclinical studies.
Despite its maturity, the field faces persistent methodological challenges. These include trade-offs between spatial resolution, temporal resolution, and signal-to-noise ratio; motion artifacts and physiological noise; standardization and reproducibility across scanners and sites; accessibility of advanced pulse sequences; and the growing complexity of data processing, quantification, and interpretation. Rapid developments in quantitative MRI, functional and diffusion imaging, spectroscopic methods, ultra-high-field MRI, accelerated acquisition techniques, and AI-assisted reconstruction further underscore the need for clear, reproducible protocols.
The goal of this Collection is to provide a centralized resource covering the full spectrum of contemporary MRI techniques that emphasize experimental design, acquisition, optimization, and validation across preclinical and clinical settings.
By emphasizing practical workflows and reproducibility, the collection will support knowledge transfer, facilitate methodological adoption, and accelerate innovation. Ultimately, this resource will benefit the scientific community by lowering technical barriers, promoting standardization, and enabling more robust and comparable MRI-based research across disciplines.
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Cited by 5
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2023
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Rani Ashouri1, Brianna Nguyen1, Jeremy Archer2, Paul Crispen1, Padraic O’Malley1, Li-Ming Su1, Joseph Grajo1,3, Sara M. Falzarano4, Yahya Acar5,6,7, David Lizdas5,6, Samsun Lampotang1,5,6, Wayne Brisbane1,6
1Department of Urology, University of Florida College of Medicine, 2Division of Urology, North Mississippi Medical Center, 3Department of Radiology, University of Florida College of Medicine, 4Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, 5Department of Anesthesiology, University of Florida College of Medicine, 6Center for Safety, Simulation & Advanced Learning Technologies, University of Florida, 7Department of Emergency Medicine, Gulhane School of Medicine