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TOPICAL COLLECTIONS

Current Methods in Magnetic Resonance Imaging

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Kang Du

Kang Du

University of Pennsylvania

Kang Du received a BS degree in Biochemistry from the University of California, San Diego, in 2012. He obtained PhD degree from Northwestern University in 2018, under the supervision of Prof. T. David Harris. In his graduate research, Kang studied transition metal complexes with unique magnetic and electronic properties, which can inspire novel and responsive 1H magnetic resonance (MR) sensors. Currently, Kang is a postdoctoral associate in the laboratory of Prof. Ivan J. Dmochowski at the University of Pennsylvania. In his postdoctoral research, Kang is studying host-guest chemistry in metal-organic capsules and exploring the potential application of these capsules as hyperpolarized 129Xe MR sensors.

Collection Overview

Magnetic resonance imaging (MRI) remains one of the most versatile and powerful noninvasive imaging modalities in modern research and clinical practice, enabling detailed structural, functional, and molecular characterization of biological systems without ionizing radiation. Continuous advances in hardware, pulse sequence design, acquisition strategies, and computational analysis have expanded MRI well beyond conventional anatomical imaging, making it indispensable across neuroscience, oncology, cardiology, musculoskeletal research, and preclinical studies.


Despite its maturity, the field faces persistent methodological challenges. These include trade-offs between spatial resolution, temporal resolution, and signal-to-noise ratio; motion artifacts and physiological noise; standardization and reproducibility across scanners and sites; accessibility of advanced pulse sequences; and the growing complexity of data processing, quantification, and interpretation. Rapid developments in quantitative MRI, functional and diffusion imaging, spectroscopic methods, ultra-high-field MRI, accelerated acquisition techniques, and AI-assisted reconstruction further underscore the need for clear, reproducible protocols.


The goal of this Collection is to provide a centralized resource covering the full spectrum of contemporary MRI techniques that emphasize experimental design, acquisition, optimization, and validation across preclinical and clinical settings.


By emphasizing practical workflows and reproducibility, the collection will support knowledge transfer, facilitate methodological adoption, and accelerate innovation. Ultimately, this resource will benefit the scientific community by lowering technical barriers, promoting standardization, and enabling more robust and comparable MRI-based research across disciplines.

Articles

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Cited by 5

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2023

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