Lately, there has been a continuing interest in discovery of new molecular and cellular mechanisms of neurodevelopment and brain aging which play an important role in the pathogenesis of neurodevelopmental and neurodegenerative disorders. These brain disorders are considered to be great public health burden, negatively impacting millions of people worldwide, and causing severe disabilities and increased morbidity. Numerous biological processes in brain on all levels from molecular to systemic carry an important role in the brain development and pathogenesis of neurodegenerative and neurodevelopmental disorders, including nervous system disabilities, sensory-related disabilities, metabolic disabilities, and degenerative disorders, Alzheimer's disease, Huntington's disease, Parkinson's disease, different types of palsy and atrophy, etc. Studying these biological processes is of great importance for neurobiology and aging research. The focus of the special issue is innovative in vivo and in vitro approaches, methods, and techniques aimed to uncover the mechanisms of neurodevelopment and brain aging.

The objective is to describe, share, and promote broader access to new approaches of neurobiological research and methods. We believe that the worldwide collaboration of neuroscientists will help to conquer and alleviate some of the most devastating brain diseases.