Current Translational Methods in Ophthalmic Research

TOPICAL COLLECTIONS

Guest Editor

Anastasiya Vinokurtseva

The University of Toronto, Department of Ophthalmology and Visual Sciences; 2. Prism Eye Institute, Glaucoma and Advanced Anterior Segment Surgery

Dr. Anastasiya Vinokurtseva is a graduate of the Schulich School of Medicine, Western University, in London, Canada, where she conducted extensive research into post-operative wound healing to improve glaucoma surgery outcomes under the guidance of Dr. Cindy Hutnik. She is currently a Research Fellow in Glaucoma and Advanced Anterior Segment Surgery at the Prism Eye Institute and Department of Ophthalmology and Vision Sciences, University of Toronto, under the mentorship of Dr. Ike Ahmed. She is pursuing a career goal of becoming a clinician scientist. She has a keen research interest in the medical and surgical management of glaucoma and its pathophysiology, as well as the development of novel ophthalmic therapies.

Collection Overview

Glaucoma is the leading cause of irreversible blindness worldwide. Elevated intraocular pressure remains the main known modifiable risk factor; however, the exact cause of this optic neuropathy remains unknown. Current interventions focus on improving aqueous humor outflow via medical or surgical means.

Several research avenues are being explored to gain a better understanding of the pathophysiology of glaucoma, including the anterior and posterior segments of the eye to learn more about the trabecular meshwork physiology, alternative outflow pathways for aqueous humor, fibrosis associated with failed filtering surgeries, and the degeneration, regeneration, and protection of retinal ganglion cells and optic nerves.

This Methods Collection aims to share a standardized methodology for current protocols in translational research and provide an overview of novel treatment options in this field.