Angiogenesis, neurogenesis, and neuroplasticity are essential biological processes that are crucial in maintaining and regulating the brain's physiological and functional health. The goal of studying angiogenesis is to understand how blood vessels are formed and maintained and how this process can be modulated to promote tissue repair and regeneration. In health, angiogenesis is a fundamental process that enables oxygen and nutrient delivery to tissues, whereas, in disease, it can contribute to tumor growth and metastasis.

The study of neurogenesis aims to understand how new neurons are generated and integrated into existing neural networks. In the healthy adult brain, neurogenesis occurs in specific regions, such as the hippocampus, and is thought to play a role in learning and memory. Researchers studying neurogenesis aim to understand the mechanisms that regulate this process and develop therapies to promote regeneration. Finally, neuroplasticity refers to the brain's ability to adapt and reorganize in response to environmental stimuli. This process is crucial for learning, memory, and recovery after brain injury.

In recent years, significant progress has been made in characterizing the processes of angiogenesis, neurogenesis, and neuroplasticity and their roles in health and disease. This Methods Collection aims to highlight various methods of studying these processes, including in vivo models in zebrafish and mice, in vitro cultivation models, and functional studies. The goal is to provide an overview of important methods that can help identify potential therapeutic targets and promote regeneration and recovery after injury or disease.