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Biofluid-Based Metabolomics
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Raquel Cumeras

Raquel Cumeras

Institut d’Investigació Sanitària Pere Virgili (IISPV), Oncology Department

Dr. Raquel Cumeras is the Head of the Advanced Metabolomics team at GIOTEC groups from IISPV, Spain. She is also affiliated to the Metabolomics interdisciplinary group at the Universitat Rovira i Virgili, Spain. Her Ph.D. thesis in Physics in 2013 received the Outstanding Ph.D. thesis award. After her PhD studies on Microelectronics sensors, she acquired Metabolomics expertise in abroad 45-months stages in the USA, partially thanks to being awarded a competitive European Marie Skłodowska–Curie fellowship. She is chair of the mQACC reference and test materials working group. Her research lines are: (1) unravel the interplay between genome, metabolome, and microbiome in the diagnosis and prognosis of colorectal cancer; (2) human biofluids multi-omics database: Life Fluids DB; (2) creation of software and tools, like the Amanida solution for meta-analysis, the GcDuo algorithm for GCxGC-MS data.

Maria Llambrich

Maria Llambrich

Universitat Rovira i Virgili (URV), Department of Electrical Electronic Engineering and Automation

Maria Llambrich is a PhD student at the Department of Electronic, Electric and Automatic Engineering in Universitat Rovira I Virgili (URV), Spain. She was educated in Biochemistry and Molecular biology, with a MSc in Omics Data Analysis. Her research is focused on advanced metabolomics applied to colorectal cancer. She is involved in gas-chromatography/mass spectrometry for volatile compounds following my interests in clinical metabolomics and in the developing of new computation methods for data analysis. Her goal is to develop new tools to extract biomedical insights from omics data. 

Collection Overview

The study of biofluids has the potential to deepen the understanding of health and disease conditions, making their analysis indispensable in precision medicine. Metabolomics provides insight into small molecules, which are the end products of cellular processes and reflect the functional state of the organism. It offers valuable information about metabolic status, disease mechanisms, treatment response, and personalized therapeutic options.

This Methods Collection seeks to provide protocols and guidance for the application of metabolomics techniques to the study of biofluids, encompassing everything from methodological development to analytic workflow improvement.

Articles

Elucidating Tissue- and Plasma-Specific Proteomic Alterations in Health and Disease

Elucidating Tissue- and Plasma-Specific Proteomic Alterations in Health and Disease

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2025

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