Guest Editor
Collection Overview
Mesenchymal Stromal Cells (MSCs) and their secretome (conditioned medium or extracellular vesicles) are highly preferred candidates for therapeutics. These cells typically possess multi-directional differentiation potential and potent immunomodulatory activity. They are anti-inflammatory and can function like antimicrobials. Their capabilities have encouraged scientists to conduct numerous preclinical and a few clinical trials to assess the translational potential of MSCs in disease therapeutics. Despite these efforts, the efficacy of MSCs has been inconsistent. The intricate interdependencies involved in manufacturing, scaling up MSCs, and their infusion pose challenges in designing MSC transfusion experiments for researchers. This Methods Collection aims to assist the research community in streamlining MSC manufacturing processes.
