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Advances in Liver Cancer Diagnosis, Prevention and Treatment

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Manali Dimri

Manali Dimri

Augusta University, Georgia Cancer Center

Dr. Manali Dimri is an Assistant Research Scientist at the Georgia Cancer Center at Augusta University. Her most recent work involves identifying novel cytokines and transcription factors and investigating their specific function in liver and adipose tissues. With the combination of these investigations, she aims to gain a comprehensive understanding of their potential involvement in the initiation and progression of liver cancer and obesity-associated fatty liver disease. In August 2015, Dr. Dimri received her PhD from the Defense Research and Development Organization, affiliated with Delhi University in India followed by postdoctoral research at Cleveland Clinic in Ohio. At Cleveland Clinic, she used multidisciplinary approaches to investigate the molecular mechanisms underlying the pathogenesis of human liver diseases, including biliary atresia and nonalcoholic steatohepatitis. Dr. Dimri's research has been published in leading journals in the field, including Hepatology, and featured in invited conferences globally, including Australia, Hong-Kong, Japan, India and the United States.

Collection Overview

Liver cancer is one of the leading causes of cancer deaths worldwide. Understanding liver cancer at the cellular and molecular levels allows dissection of specific molecular targets for this fatal disorder. We are at the beginning of a new era of targeted therapeutics for the treatment of liver cancer. Despite several advanced techniques for the diagnosis and treatment of liver cancer, it is difficult to recapitulate in the laboratory setting, which is a major setback for the progression of research. Inarguably, visualization greatly facilitates the understanding and efficient reproduction of both basic and complex experimental techniques. The objective of this visual methods collection is to disseminate the innovative experiments and corresponding methodologies that apply to liver cancer and related areas. The broader vision is to promote practical learning among peers in the scientific community and provide global access to reproducible skills pertaining to the field of cancer.

Articles

A Hepatocellular Cancer Patient-Derived Organoid Xenograft Model to Investigate Impact of Liver Regeneration on Tumor Growth
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A Hepatocellular Cancer Patient-Derived Organoid Xenograft Model to Investigate Impact of Liver Regeneration on Tumor Growth

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2024

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