
Organoids have emerged as powerful three-dimensional (3D) culture systems that recapitulate key structural and functional aspects of human tissues. These self-organizing structures, derived from pluripotent or adult stem cells, provide an advanced platform for studying disease mechanisms, drug responses, and regenerative medicine.
This special issue aims to highlight the latest advancements in tissue organoid technology for disease modeling, covering a broad range of applications, including neurodegenerative disorders, cancer, infectious diseases, and genetic syndromes. We welcome contributions on novel bioengineering strategies, patient-derived organoid models, high-throughput drug screening, and mechanistic insights into disease pathology.
Key Topics Include:
· Innovations in organoid culture techniques and biomaterials
· Organoid-based models for complex diseases
· Integration of organoids with CRISPR gene editing, omics technologies, and microfluidic systems
· Translational applications in personalized medicine
By bringing together experts in stem cell biology, bioengineering, and disease modeling, this issue will explore how organoid-based platforms are revolutionizing biomedical research and paving the way for more precise therapeutic strategies.