Collection-image

TOPICAL COLLECTIONS

Neurobiology of Disease: Cellular Mechanisms and Biomarker Discovery
Submit Abstract

Guest Editor

Elnaz Amanzadeh Jajin

Elnaz Amanzadeh Jajin

Department of Cell and Molecular Biology and Microbiology, Faculty of Biological Science and Technology, University of Isfahan

Dr. Elnaz Jajin is a senior researcher at the University of Isfahan, with a PhD in Cell and Molecular Biology. A neuroscientist by training, Dr. Jajin specializes in studying neurodegenerative diseases and glioblastoma using a multidisciplinary approach that integrates behavioral studies, molecular biology, clinical evaluations, and computational tools for omics data analysis. With a strong belief that cell function holds the key to understanding progressive neurological conditions, Dr. Jajin is committed to advancing research that reveals the underlying mechanisms of disease and informs therapeutic innovation.

Collection Overview

Neurological diseases, including neurodegenerative disorders and brain tumors such as glioblastoma, continue to pose significant global health challenges. Understanding the cellular and molecular mechanisms that drive these conditions is essential for identifying novel biomarkers, achieving earlier diagnoses, and developing targeted therapies.

This Methods Collection aims to highlight innovative methodologies in cell and molecular neurobiology that deepen our understanding of neurological disease pathogenesis. We welcome submissions focused on:

  • Molecular signaling pathways and gene expression changes in disease
  • Cellular dysfunction in neurons and glial cells
  • Bioinformatics approaches and omics-based data analysis
  • Biomarker discovery for early diagnosis or prognosis
  • Experimental models and imaging techniques used in neurobiology research

By curating both experimental and computational studies, this collection seeks to advance precision neuroscience and foster translational approaches in neurodegenerative and neuro-oncological research.

Articles

Stereotactic Intracranial Implantation of Glioblastoma Patient-derived Xenograft Cell Lines in Mice
8:24

Stereotactic Intracranial Implantation of Glioblastoma Patient-derived Xenograft Cell Lines in Mice

0 Views

•

2026

•

Abstracts

Intracranial tumor implantation

Danielle Burgenske1,

Jann Sarkaria*1

1Mayo Clinic

A Physiologically Relevant 3D iPSC-Derived Microfluidic Model of the Blood–Brain Barrier

Melanie Alpaugh*1

1Department of Molecular and Cellular Biology, SSC 3463 University of Guelph.

A Surgical Protocol for Infraorbital Nerve Chronic Constriction Injury (IoN-CCI) in Mice

Lauren Cook1,

Minghan Hu1,

Kenneth Yamada*1,

Ashok Kulkarni*1

1National Institutes of Health