Wound healing remains a significant clinical challenge, particularly in chronic or complex wounds such as diabetic ulcers, extensive burns, and post-surgical defects. Among various regenerative strategies, adipose-derived stem cells (ADSCs) have emerged as a promising tool due to their abundance, ease of harvesting, and capacity to promote tissue regeneration through paracrine signaling and immunomodulation. Recent studies have shown that ADSC-derived exosomes, gene-modified ADSCs, and combinations with electrical stimulation significantly enhance re-epithelialization and angiogenesis in preclinical wound models. 

This Methods Collection will focus on experimental and clinical protocols that utilize ADSCs in wound repair. Contributors are invited to submit protocols related to the isolation, expansion, and characterization of ADSCs and their application in various delivery forms, including cell sheets, scaffolds, and injectable formulations. We also welcome articles demonstrating advanced imaging techniques, biomaterials integration, and preclinical animal models assessing ADSC-based therapies.

The collection will benefit researchers and clinicians in regenerative medicine, plastic surgery, dermatology, and bioengineering while serving as a high-impact resource to enhance reproducibility, accelerate clinical translation, and foster cross-disciplinary innovation.