Neuromodulation has emerged as a promising therapeutic approach for a wide range of neurological disorders that are resistant to conventional treatments. Noninvasive techniques such as transcranial direct current stimulation (tDCS), transcranial magnetic stimulation (TMS), and peripheral nerve stimulation have shown potential in restoring neural network balance, enhancing neuroplasticity, and improving motor and cognitive functions, particularly in conditions such as cerebral ischemia, Parkinson's, traumatic brain injury, and epilepsy.
This Methods Collection aims to provide the neuroscience community with standardized, peer-reviewed protocols that detail the application of neuromodulation techniques in both preclinical and clinical settings. By offering high-quality, step-by-step visual demonstrations, the collection will help researchers accurately replicate experimental procedures, optimize stimulation parameters, and evaluate functional outcomes. In addition, the collection seeks to bridge the gap between experimental neurotechnology and translational neuroscience by promoting reproducibility, transparency, and methodological rigor.
Through this visual and methodological resource, researchers, clinicians, and students will gain valuable insights into implementing neuromodulation strategies and their potential for therapeutic innovation. Ultimately, this collection is expected to foster cross-disciplinary collaboration and accelerate progress in neurorehabilitation.
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2026
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1Rehabilitation Medicine Center and Institute of Rehabilitation Medicine, West China Hospital, Sichuan University, 2Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, 3The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Institute of Health and Rehabilitation Science, School of Life Science and Technology, Xi’an Jiaotong University
A multimodal approach to assess non-motor TMS effects.
Francis Houde1,
Guillaume Leonard*1
1Research Centre on Aging
Temporal interference (TI) stimulation of the cerebellar fastigial nucleus
Lin He1,
Yixin Wei2,
Chaoran Gao2,
Shutao Qiu2,
Tian Liu*3,
Qiang Gao*2
11.Rehabilitation Medicine Center and Institute of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu 610041, China ; 2.Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu 610041, China,
21.Department of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 2.Key Laboratory of Rehabilitation Medicine in Sichuan Province, West China Hospital, Sichuan University, Chengdu, People’s Republic of China,
3The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Institute of Health and Rehabilitation Science, School of Life Science and Technology, Xi’an Jiaotong University, Xi’an 710049, China.