

Rui Gu
School of Ethnic Medicine, Chengdu University of Traditional Chinese Medicine
Dr. Rui Gu is a professor, doctoral supervisor, and the dean of the School of Ethnic Medicine at Chengdu University of Traditional Chinese Medicine. He is a recognized academic leader in Traditional Chinese Medicine in Sichuan Province and holds key leadership roles, including vice president of the resources branch of the Chinese Society of Ethnic Medicine.Dr. Gu’s research focuses on the sustainable use of ethnic medicine resources. His work integrates artificial intelligence (AI) and UAV remote sensing for medicinal plant assessment, promotes the conservation of endangered species on the Tibetan Plateau, and supports the standardization and industrialization of Tibetan medicines. He has secured five grants from the National Natural Science Foundation of China and published over 50 research papers. Dr. Gu also holds six national patents as the first inventor and has received multiple provincial and industry awards for his scientific and technological contributions to the field.

Weifen Zhang
College of Pharmacy, Shandong Second Medical University
Dr. Weifen Zhang is a professor (Level 2), doctoral supervisor, and director of the Experimental Teaching Center at the School of Pharmacy, Shandong Second Medical University. She also leads the Institute of Intelligent Materials and Regenerative Medicine. A nationally recognized academic leader, she is a Special Government Allowance Expert of the State Council and a recipient of numerous honors, including National Outstanding Teacher and Shandong Provincial Outstanding Science and Technology Worker. Her research centers on innovative drug delivery systems and biomaterials. Dr. Zhang has led 16 research projects, including grants from the National Natural Science Foundation of China. She has received 14 major awards as the first contributor, including two Second-Class Scientific and Technological Progress Awards of Shandong Province and the China Patent Excellence Award. She has published over 110 SCI-indexed papers and holds 27 authorized national and international patents, reflecting her significant contributions to pharmaceutical sciences and biomedical innovation.

Shaohui Wang
Shandong University of Traditional Chinese Medicine, Qingdao Academy of Chinese Medical Sciences
Shaohui Wang is a professor and doctoral supervisor at the Shandong University of Traditional Chinese Medicine. He holds a PhD in ethnic minority medicine. As the director of the Yellow River Basin Ethnic Medicine Innovation Research Center, his research focuses on applying cutting-edge technologies, such as artificial intelligence and big data, to the innovative development of ethnic minority medicine in the Yellow River Basin. He has presided over two National Natural Science Foundation of China. With over 40 SCI papers published, he is dedicated to bridging traditional medicinal wisdom and modern frontier advanced technology.

Xia Ren
Qingdao Academy of Chinese Medical Sciences, Shandong University of Traditional Chinese Medicine
Dr. Xia Ren, PhD, is a postdoctoral researcher in pharmacy and a master’s supervisor. Her research focuses on developing and utilizing traditional marine Chinese medicine, with particular emphasis on pharmacodynamic material basis, quality evaluation, and the development of innovative drugs in this field. She has led and completed several scientific research projects, including those funded by the National Natural Science Foundation of China (Youth Program), the Shandong Natural Science Foundation, and the Qingdao Postdoctoral Applied Research Program. She has also participated in major national science and technology projects and key R&D initiatives in Shandong Province.Dr. Ren has applied for five invention patents and two software copyrights. She has published 20 papers as the first author, 15 of which are indexed in SCI, including seven in top-tier journals. Two of her papers have been recognized as ESI’s top 1% of highly cited papers.
The Yellow River Basin is a cradle of diverse ethnic cultures and is home to a wealth of ethnic medicinal resources, including Traditional Chinese Medicine (TCM), Mongolian medicine, Tibetan medicine, and medicinal plants found in wetlands. These resources have significant clinical value; however, they face challenges such as insufficient modernization and unclear mechanisms of efficacy.
This collection aims to illustrate how cutting-edge technologies—such as artificial intelligence (AI), multimodal omics, organoids, and nanomaterials—can help address these challenges. The focus will be on several areas, including AI-driven formula optimization, target and ingredient screening, efficacy verification and evaluation, and the exploration of underlying mechanisms.
By integrating traditional knowledge with technological innovation, this collection will provide actionable methods for the research community, facilitate the translation of ethnic medicine into clinical applications, and promote cross-disciplinary collaboration in the study of basin-specific medicinal practices. We invite original research articles, reviews, case studies, and meta-analyses on this important topic.
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Chen Luo*1,2, Yan Yang*3, Wenjie Xu*2, Lian Xia2, Daike Zou2, Junjie Deng2, Peilin He4, Xianqin Luo1,2
1College of Chinese Materia Medica, Chongqing University of Chinese Medicine, 2College of Traditional Chinese Medicine, Chongqing Medical University, 3Department of Liver Diseases, Chongqing Traditional Chinese Medicine Hospital, 4Institute of Pharmacology and Toxicology, Chongqing Academy of Chinese Materia Medica
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Zhiwei Zhang1, Min Tu2, Ning Yuan1, Wenqiang Qian1, Guopeng Wang1, Maohua Lin3, Jiefei Xie3, Li Liang1, Jian Guo1, Bin Zhang4, Shaoyong Fan1, Haiming Huang1
1Smart minimally invasive orthopedics and interventional Medicine department, Nanchang Hongdu Hospital of Traditional Chinese Medicine, 2Nanchang Hongdu Hospital of Traditional Chinese Medicine, 3Jiangxi University of Chinese Medicine, 4Department of Orthopedic Hospital, the 1st Affiliated Hospital, Jiangxi Medical College, Nanchang University
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Kehan Gao*1, Xingming Xu*1, Minyan Sun1, Siqi Zhu1, Xinyi Luo1, Jiahong Li1, Kuangyi Liu2, Hui Chen3, Xiaomin Wang1
1Top Discipline of Jiangxi Province, Discipline of Chinese and Western Integrative Medicine, Jiangxi University of Chinese Medicine, 2The Third Affiliated Hospital, Jiangxi Medical College, Nanchang University & Pharmacy Department of Nanchang First Hospital, 3The Third Affiliated Hospital, Jiangxi Medical College, Nanchang University & Cardiovascular Department of Nanchang First Hospital
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Shaohui Wang*1,2, Guoying Liu*1, Yu Zhang*3, Yuying Li3, Chunxia Zhang1, Zixian Chen2, Rongying He5, Dongsheng Ren3, Jiyu Tong5
1Qingdao Academy of Chinese Medicinal Sciences, Shandong University of Traditional Chinese Medicine, 2State Key Laboratory of Southwestern Chinese Medicine Resources, School of Ethnic Medicine, Chengdu University of Traditional Chinese Medicine, 3Tibet Rhodiola Pharmaceutical Holding Co. Ltd, 4State Key Laboratory of Southwestern Chinese Medicine Resources, School of pharmacy, Chengdu University of Traditional Chinese Medicine, 5Laboratory of Epigenetics and Immunology, West China Institute of Women and Children's Health, NHC Key Laboratory of Chronobiology, Department of Obstetric and Pediatric, Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University
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Huijing Li*1, Shuang Li*1, Disi Deng2, Min Liu2, Ranran Gao3, Jiawei Li4, Juan Li5, Xiaojin Huang6, Yuling Zuo7, Yeke Wu7
1College of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, 2Department of Gynaecology, Hospital of Chengdu University of Traditional Chinese Medicine, 3Department of Traditional Chinese Medicine, Henan Provincial People's Hospital, Zhengzhou University, 4College of Basic Medical Sciences, Chengdu University of Traditional Chinese Medicine, 5College of Health and Rehabilitation, Chengdu University of Traditional Chinese Medicine, 6State Key Laboratory of Oral Diseases, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Department of Traditional Chinese Medicine, West China Hospital of Stomatology, Sichuan University, 7Department of Stomatology, Hospital of Chengdu University of Traditional Chinese Medicine
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1Hemodialysis Room, Hospital of Traditional Chinese Medicine of Qiqihar, 2Department of Nephrology, Ezhou Central Hospital, 3Department of Integrated Traditional Chinese and Western Medicine, The First Hospital of Qiqihar, 4Department of Nephrology, Shanghai Minhang Hospital of Integrated Traditional Chinese and Western Medicine
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1Innovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, 2Department of Pharmacy, The Affiliated Hospital of Shandong University of Traditional Chinese Medicine, 3Shandong Key Laboratory of Innovation and Application Research in Basic Theory of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine