Collection-image

TOPICAL COLLECTIONS

Translational Preclinical Laboratory Techniques in Vascular Biology
Submit Abstract

Guest Editors

Daniel R. Machin

Daniel R. Machin

Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center

Dr. Daniel Machin is an assistant professor in the Department of Cell Biology and Physiology at the University of New Mexico School of Medicine, where he is part of the Vascular Physiology Group within the department. His research expertise is in cardiovascular physiology and vascular biology. The goals of his laboratory are to investigate and elucidate the physiological, cellular, and molecular mechanisms responsible for endothelial dysfunction in advanced age and disease, as well as to identify novel therapeutics that can ameliorate age- and disease-related vascular dysfunction.

Olan Jackson-Weaver

Olan Jackson-Weaver

Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center

Dr. Olan Jackson-Weaver is an assistant professor in the Vascular Physiology Group of the Department of Cell Biology and Physiology at the University of New Mexico School of Medicine. His research expertise is in the vascular effects of trauma, hemorrhage, and acute illness. His work investigates the mechanisms of acute endothelial glycocalyx damage and repair and the role of these processes in coagulopathy, inflammation, organ failure, and vascular autoregulation. Recent work has uncovered roles for endothelial succinate metabolism in regulating these processes.

Mostafa Sabouri

Mostafa Sabouri

Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center

Mostafa Sabouri is a PhD candidate in the Department of Cell Biology and Physiology at the University of New Mexico, conducting research under the mentorship of Dr. Daniel Machin. His research targets the mechanisms of vascular dysfunction, with a focus on endothelial glycocalyx biology and arterial health. His background includes a B.S. in Kinesiology and an M.S. in Exercise Physiology, with experience in molecular biology, animal models, and translational cardiovascular research. His current work investigates diet- and age-related changes in the vascular glycocalyx, integrating genetic mouse models to identify mechanistic drivers and potential therapies for cardiovascular disease. Mostafa has also contributed as a manuscript reviewer and has been recognized for research excellence and scientific engagement in the field of physiology.

Lunden Friberg

Lunden Friberg

Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center

Lunden Friberg is a doctoral student in the Department of Cell Biology and Physiology at the University of New Mexico in Albuquerque. He is studying endothelial dysfunction associated with blood cholesterol dysregulation and is expanding methods to assess endothelial glycocalyx integrity. Lunden graduated in 2023 with a B.S. in Health Sciences from Purdue University in West Lafayette, Indiana. He joined the Machin Laboratory in February 2025 as part of the University of New Mexico Biomedical Sciences Graduate Program and brings broad experience in cardiovascular physiology.

Collection Overview

We propose a collection of video tutorials on in vivo and ex vivo translational preclinical vascular biology techniques demonstrated by experts in their respective fields. Several vascular biology techniques are well established but practiced in only a limited number of laboratories. The goal of this collection is to streamline the learning of these techniques through video demonstrations that provide clear, step-by-step guidance. This collection will help demystify the complex procedures involved and support broader adoption across laboratories.

Articles

Assessing Murine Aortic Intrinsic Stiffness Using Pin Myography: A Translational Framework For Interrogating The Influence of the Circulating Milieu
5:57

Assessing Murine Aortic Intrinsic Stiffness Using Pin Myography: A Translational Framework For Interrogating The Influence of the Circulating Milieu

0 Views

•

2026

•