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TOPICAL COLLECTIONS

Standardized Animal Models of Abdominal Trauma for Mechanistic Studies and Therapeutic Evaluation
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Guest Editors

Xingshun Qi

Xingshun Qi

Department of Gastroenterology, General Hospital of Northern Theater Command

Dr. Xingshun Qi obtained his medical doctoral degree from the Fourth Military Medical University and completed his postdoctoral fellowship at the General Hospital of the Shenyang Military Area Command. He is currently the Head of the Department of Gastroenterology at the General Hospital of the Northern Theater Command. His primary research interests include the etiology, diagnosis, and management of liver cirrhosis, portal hypertension, portal vein thrombosis, Budd–Chiari syndrome, and hepatocellular carcinoma.Dr. Qi serves as a senior editorial board member of BMC Gastroenterology, an editorial board member of Advances in Therapy and Therapeutic Advances in Gastroenterology, and an academic editor for the Canadian Journal of Gastroenterology and Hepatology and the Journal of Clinical and Translational Hepatology. His current h-index is 56.

Xiaodong Shao

Xiaodong Shao

Department of Gastroenterology, General Hospital of Northern Theater Command

Dr. Xiaodong Shao graduated in medicine from the Fourth Military Medical University (FMMU), China, in 1995 and obtained his PhD in medicine from the same institution in 2005. He is currently a professor in the Department of Gastroenterology at the General Hospital of the Northern Theater Command, China. His primary area of expertise is gastrointestinal endoscopy.Dr. Shao has authored more than 40 peer-reviewed publications and contributed five book chapters. He has served as both principal investigator and co-principal investigator on numerous research projects. Additionally, he is an active member of the Chinese Society of Gastroenterology and the Chinese Medical Doctor Association.

Collection Overview

Abdominal trauma, including penetrating, blunt, and blast-related injury patterns, triggers complex, system-wide physiologic responses ranging from hemorrhage to infection and organ dysfunction, highlighting the need for well-controlled, reproducible experimental models. Despite extensive laboratory work, many abdominal trauma animal models are difficult to reproduce because key technical details, such as injury induction and calibration, physiologic monitoring, resuscitation strategies, and outcome measures, are inconsistently reported, limiting cross-study comparison and slowing translation.

 

This Topical Collection aims to provide rigorous, step-by-step methodological protocols for standardized induction of abdominal trauma in animal models, spanning solid-organ injuries, hollow viscus injuries, as well as intervention protocols and outcome assessment. Submissions are encouraged that clearly define injury severity and reproducibility (including grading systems and calibration approaches), periprocedural care (including anesthesia, analgesia, antibiotics, humane endpoints), and monitoring parameters (hemodynamics, laboratory markers, imaging, functional assessments, and histopathology).

 

By providing detailed, standardized protocols, this collection will enhance the reproducibility and help investigators choose and adapt the most appropriate model for their specific scientific question. Ultimately, these shared protocols will accelerate mechanistic discovery and therapeutic evaluation in abdominal trauma, supporting more rigorous, ethical, and translatable laboratory research.

Articles

Selective Non-Operative Management After Abdominal Gunshot and Blast Injuries in A Porcine Model

Selective Non-Operative Management After Abdominal Gunshot and Blast Injuries in A Porcine Model

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2026

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