
Tumor heterogeneity and drug resistance remain central challenges in modern clinical oncology, underscoring the urgent need for precision diagnostics and more effective therapeutic strategies to improve patient outcomes. This collection systematically highlights recent advances in cutting-edge diagnostic technologies, such as liquid biopsy and molecular imaging; refined prognostic prediction approaches, including bioinformatics-driven analyses and well-curated clinical cohort studies; and innovative therapeutic modalities encompassing targeted therapies, immunomodulatory strategies, and rational combination treatments. By integrating multidisciplinary methodologies, the collection aims to accelerate the translation of basic research discoveries into clinical applications. It will provide critical insights for both researchers and clinicians, support the optimization of personalized treatment regimens, and facilitate the rapid clinical adoption of breakthrough advances in cancer diagnosis and therapy.
Integrative Pan-Cancer Multi-Omics Analysis Identifies KRT81 as a Diagnostic, Prognostic, and Immunotherapeutic Biomarker
Tong Liu*1
1 Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine
A Bioinformatics Framework for Developing a Cancer-Associated Fibroblast Prognostic Signature in Glioma
Yong Wang*1
1Yanbian University Hospital
Multi-omics Integration Reveals the Diagnostic Value of THBS2 and Its Role in Microenvironmental Remodeling in OLP and OSCC
Liyuan Wang1
1General Hospital of Ningxia Medical University
From Tumor Suppressor to Tumor Promoter – The Dual Role of LIMCH1 in Cancer and Its Clinical Implications
Ying Li1
1Jilin Medical University
Integrated multi-omics investigation of the ferro-aging pathway in glioblastoma
Huiying Li*1
1Beihua University