Adverse childhood experiences (ACEs) are a major transdiagnostic risk factor for the development of psychopathology across the lifespan. Yet, assessing ACEs and their developmental consequences precisely remains a significant challenge. Definitions of adversity vary widely across studies, and researchers employ diverse measurement tools and outcome indicators. This inconsistency contributes to conflicting findings and hampers progress toward mapping clear risk and resilience pathways following early adversity. To enhance replicability and facilitate cumulative knowledge building in the field, greater methodological alignment is needed.

This collection highlights current methods used to assess ACEs and to measure their developmental, behavioral, and neurobiological consequences. By showcasing approaches spanning human and rodent research, the collection aims to promote transparency, comparability, and innovation in the study of childhood adversity and its impact on mental health.